(-)-ephedrine; (1R,2S)-(-)-ephedrine; ephedrine; l-ephedrine; (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol | |
Links: | 🌍 Wikipedia, 📏 NIST |
MeSH: | Adrenergic Agents; Autonomic Agents; Central Nervous System Agents; Central Nervous System Stimulants; Neurotransmitter Agents; Vasoconstrictor Agents |
CAS RN: | [299-42-3] |
Formula: | C10H15NO; 165.24 g/mol |
InChiKey: | KWGRBVOPPLSCSI-WPRPVWTQSA-N |
SMILES: | CN[C@@H](C)[C@H](O)c1ccccc1 |
Pharmaceutical use: | adrenergic; antiepileptic; antitussive; bronchodilator; cardiostimulant; hypertensive; mydriatic; vasopressor |
Toxicology (LD50): | 61.0 mg/Kg (cat, iv); 74.0 mg/Kg(cat, iv); 73.0 mg/Kg(dog, iv); 220 mg/Kg(dog, sc); 600 mg/Kg(frog, sc); 610 mg/Kg(frog, sc); 400 mg/Kg(guinea~pig, sc); 412 mg/Kg(guinea~pig, sc); 400 mg/Kg(mouse, ip); 200 mg/Kg(mouse, iv); 400 mg/Kg(mouse, or); 300 mg/Kg(mouse, sc); 1 000 mg/Kg(mouse, sc); 340 mg/Kg(rabbit, im); 355 mg/Kg(rabbit, ip); 61.0 mg/Kg(rabbit, iv); 69.0 mg/Kg(rabbit, iv); 590 mg/Kg(rabbit, or); 360 mg/Kg(rabbit, sc); 380 mg/Kg(rabbit, sc); 800 mg/Kg(rat, ip); 137 mg/Kg(rat, iv); 160 mg/Kg(rat, or); 1 500 mg/Kg(rat, sc) |
Density: | 1.124 g/mL |
Molar volume: | 147.0 mL/mol |
Melting point: | 36 °C |
Boiling point: | 225 °C |
Log10 partition octanol / water: | 1.13 |